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If you switch narrative tone, it will distance the reader and make it harder for him or her to achieve suspension of disbelief. If you are writing a post-modernist novel, or a post-post-modernist novel (say, a fable about life in a you-tube-saturated short-attention-span society), this might be a good thing. Otherwise, it is probably something to avoid.
You could get away with drastically different tones if you had two different POV narrators. If one is Tina Fey and the other is Sylvia Plath, they will of course see the world differently. The contrast will probably make your book lean more towards humor/dark humor/satire, so as long as you're okay with that, give it a shot. This is not the same as a ...
You don't want to break the reader's immersion. With your writing, you build the reader's identification with your characters and his expectations about the future progress of the story. If your characters suddenly act out of character, they become unbelievable. If you story progresses in a random fashion, your readers will be confused. Sure, life isn't ...
In Shakespeare's Othello, Othello's speech often changes tone between scenes. He often sees himself as uncivilized however his tough is quite the contrary. However, in some scenes his language becomes more "brutal". This was just an example, I think that changing the tone of dialogue in a character can both allow the reader to identify the mood of a ...
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