I'd recommend going to PODW and walking through their instant quote wizard. It will give you an excellent appreciation of the sorts of decisions that you have to make, and an idea of the costs.
If you went for some traditional book printer you'd probably get a better price, but the effort of dealing with them would make you wish for an early and painless death.
(I have a publisher sitting next to me, and boy the stories I hear ...)
Anyway, PODW seem like an efficient bunch of people.
(I just looked at picture.com prices and nearly fell off my chair).